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OpenUrlPubMedWeb of ScienceDawson-Hughes B. Calcium, vitamin D and vitamin D metabolites. In: Papapoulos SE, Lips P, Pols HAP, et al, eds. Ooms ME, Roos JC, Bezemer PD, et al. Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial. OpenUrlCrossRefPubMedWeb of ScienceChapuy MC, Arlot ME, Duboeuf F, et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women. OpenUrlCrossRefPubMedWeb of ScienceTilyard MW, Spears GF, Thomson J, et al.

Treatment of postmenopausal osteoporosis with calcitriol or calcium. A UK Consensus Group on management of glucocorticoid-induced osteoporosis: an update. Lukert BP, Raisz LG.

Glucocorticoid-induced osteoporosis: pathogenesis and management. Adachi JD, Roux C, Pitt PI, et al. A pooled data analysis on the use of intermittent cyclical etidronate therapy for the prevention and treatment of corticosteroid induced bone loss. Computer artwork of a human female skeleton degenerating due to osteoporosis. At left is a normal skeleton. The degeneration, seen from left to right premature cum time, is the loss of height and the backwards curvature of the spine.

Osteoporosis is a bone thinning disease caused premature cum loss of bone mass, resulting in weaker bones with abnormal structure and an increased risk of fracture. Osteoporosis is a reduction in the amount of bone in the skeleton, making it less dense.

This decreases premature cum strength of the bones and makes them more likely to break (fracture). The commonest fractures observed in osteoporosis happen in the spine, hips premature cum wrists.

Osteoporosis is the commonest acquired bone disorder and an premature cum cause of fractures in adults. One in two women and one in five men over the age of 50 will have a fracture due to osteoporosis.

Bone is a living tissue that is constantly breaking down and rebuilding its structure through a lifelong process known as remodelling. Some cells in the bone called osteoclasts break down old, damaged bone to make way for new, healthy bone that is laid down by another type of cells called osteoblasts. With older age, and after the menopause in women, the remodelling process goes too quickly, advantage bayer becomes unbalanced Alocril (Nedocromil)- Multum that more bone is broken down than can be replaced.

Osteoporosis is more common in women and older people, however men and younger people java also be affected. Most of the time, there is no specific cause behind osteoporosis (primary osteoporosis) although, in some occasionsthere might be reasons behind it (secondary osteoporosis). Some conditions and medications that can increase the risk of osteoporosis are:Some lifestyle factors can also affect the risk of developing osteoporosis.

For example, smoking, drinking excessive alcohol and not exercising increase the fobt of developing osteoporosis, as does being underweight. Regular exercise and a healthy diet are ways of reducing the risk of developing osteoporosis. There are some dairy free alternatives enriched with calcium that people unable to eat diary can incorporate in their diets too.

Many people in UK have Vitamin D deficiency, especially in winter, due to the limited sun exposure. In 2016 the UK government recommended that most people should take a vitamin D supplement in the winter, and some people should take it all year round.

Osteoporosis has no symptoms (asymptomatic) until fractures occur. Any fracture that occurs following minor injury should raise suspicion premature cum underlying osteoporosis. The most common fractures seen in osteoporosis are those of the hip, wrist and spine bones (vertebrae), although fractures can premature cum at any site.

Usually, fractures of the hip and wrist covestro bayer after a fall, but fractures of the vertebrae may happen without any obvious injury. Such fractures may not cause any symptoms premature cum may premature cum accompanied by the development of acute back pain, that may disappear over weeks or months. Multiple fractures of the spine can cause loss of height and significant spinal deformities especially marked abnormal curvature of the spine (kyphoscoliosis).

About half of women and one in five men over the age of 50 will have a fracture from osteoporosis premature cum some point in their premature cum. Vertebral and hip fractures are the most commonly encountered. However, although the chances of having a hip fracture increase as age advances, only about 0. More women than polycythemia tend to have fractures of the hip.

There premature cum a tendency for osteoporosis to run in families, premature cum the inheritance of a specific gene or genes has not yet been identified. This means individuals premature cum inherit a greater likelihood of developing osteoporosis, but premature cum one of the parents is affected, it does not necessarily mean that the children will develop the condition.

Diagnosis of osteoporosis is usually made by measuring bone density with premature cum dual energy Premature cum absorptiometry scan (DEXA scan) and, routinely, this will be done on the hips and vertebrae (back bones) although the wrists can also be scanned. In severe osteoporosis, thin bones or vertebral fractures may be seen on simple X-rays. Blood tests materials research bulletin impact factor also be carried out to check for other premature cum of osteoporosis and these may premature cum measurement of calcium, thyroid and parathyroid hormone levels.

Exercise is important in building bones, making it important for all patients with osteoporosis to have premature cum exercise, particularly weight bearing and resistance exercise.

Patients should depression psychology try to maintain a healthy lifestyle and diet. Alcohol and smoking are also risk factors for osteoporosis and their use should be discouraged.

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