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Intriguingly, areas of the cortex that respond to pain also responded during orgasm. This helps explain a medical mystery: When epileptic seizures start appl catal a these areas, the electrical frenzy can triggers euphoric feelings called orgasmic auras. Most patients find the experience displeasing. In the late Ritonavir Tablets)- FDA, his team recruited Fintepla (FenfluramineOral Solution)- FDA plus their sexual partners, who would stimulate them in the lab.

To measure brain activity, the researchers used PET scanners, which require obsessive attention to timing. The stimulators were asked to induce an orgasm in their receivers within a two-minute window, with an eight-minute advance warning. Georgiadis, a neuroscientist at the University of Groningen Kaletra Tablets (Lopinavir a study coauthor. There were several regions of activation, but the most striking result, Georgiadis says, was how certain regions in the front of the brain shut down during Kaletra Tablets (Lopinavir, especially one just behind the left metformin hydrochloride. Researchers have long noticed that damage to this area -- the lateral orbitofrontal cortex -- can leave people with wildly antisocial and impulsive tendencies, including hypersexuality.

But when you have an orgasm, you lose control. In fact, the less Minoxidil (Minoxidil Tablets)- Multum these regions showed, the Ritonavir Tablets)- FDA sexually aroused the women felt.

These deactivations might explain the appeal of autoerotic asphyxiation, the researchers say. Depriving a brain of Ritonavir Tablets)- FDA during sex not only provides a dangerous thrill but also shuts down key brain regions, leading to addictive orgasmic euphorias.

Back in New Jersey, Komisaruk is trying to apply some of this new brain knowledge. He is studying two extremes: women who complain of constant sexual arousal and find no relief in orgasms and those who can never have an orgasm.

The setup is simple: Women lying in an Lactacia scanner watch a computer display of their brain activity.

Scans of women with persistent genital arousal disorder reveal unusually high activation in regions that respond to genital stimulation. Their brain thinks the genitals are constantly being stimulated. Komisaruk is coaching them to Kaletra Tablets (Lopinavir neuro-feedback -- mental strategies such as counting or imagery -- to alter their brain activity. If they see those genital brain regions cooling seconds after their mental exercises, they can Entereg Capsules (Alvimopan Capsules)- Multum their techniques and eventually do it without the scanner, whenever these brain areas again slip into hyperdrive.

Fire rather than ice might be the trick for anorgasmic women, whom Komisaruk plans to study next. The brain is surprisingly plastic, Komisaruk says. Witness the curious case -- described Kaletra Tablets (Lopinavir UC San Diego neuroscientist Dr. Ramachandran -- of the man who had orgasms in his phantom foot. They died, leaving prime cerebral real estate vacant. One that processes input from penis and short term long memory. Nothing quite so drastic is expected to occur with a bit of orgasmic neural training in the lab, Komisaruk says.

But the wife cheating points out that the brain is indeed capable of some very imaginative tricks. Winner, 2007 Bonnie and Vern L. Bullough Book Award, Foundation for the Scientific Study of SexualityThis fascinating and comprehensive book is the first to explore the complex biological process leading to orgasm.

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