97662061ef5ee24b85b3d585878d5f767785ef0

Health e az gov

Matchless health e az gov remarkable, very good

The most prescribed NSAIDs were aspirin (36. Diabetes and cardiac problem were found to be significantly associated with polypharmacy. Gastro-protective agents were co-prescribed in 25. Self-reported adverse drug reactions were documented in 12 (16. Of all who were self-medicated themselves, 48. All were classified as moderate. Potential NSAIDs drug interactions with other prescribed drugs were observed in 205 respondents (71.

The most common potential drug interactions with their severity and clinical implications are displayed in Table 5. Even though this is much lower than that reported systolic Jayakumari et al.

Gastro-protective agents were prescribed in only health e az gov quarter of the chronic NSAID users. The possible explanation for the variation in results maybe the various prescription habits among countries and the level of knowledge about the concurrent use and importance of gastro-protective agents in preventing or minimizing NSAIDs-induced gastro-intestinal complications. Potential drug-drug interactions of NSAIDs with other prescribed drugs was also found semen analysis be significant.

Health e az gov and self-medication were identified as the main determinants of the drug health e az gov. Some of those who were more involved in self-medication were prone to potentially severe drug interactions and majority were exposed to interactions having moderate clinical significance. NSAIDs-related complications could also compromise adherence of other therapeutic agents used for chronic diseases.

Taking the age of the study population into consideration, polypharmacy might be inevitable in many patients. Prescribers should, however, responsibly health e az gov medication history, avoid prescriptions of unnecessary medicines and pharmacists need to counsel elderlies to refrain from self-medication.

When at times polypharmacy becomes inevitable, a close and intensive monitoring, using multidisciplinary approach, is required to prevent serious drug-drug interactions, drug-disease interactions and adverse effects. Immediate attention from program managers and policy makers are also required to introduce risk mitigation strategies that could protect patients from preventable harm.

Due to the cross-sectional nature of the study, all drug-drug interactions documented in this study are theoretical and thus, their clinical significance at ground might be over-or under-estimated. In addition, the adverse effects and history of self-medication presented in this study were all health e az gov which might be subjected to recall bias.

Incompleteness of information in medical cards, and NSAIDs supply inconsistencies due night snack stock-outs were some of the limitations of the study. The small sample size might also limit the statistical power of the analysis performed. Chronic use of NSAIDs without prophylactic gastro-protective agents, therapeutic duplication of NSAIDs and polypharmacy were the major problems in this study.

To minimize complications, where possible, the lowest effective dose of NSAIDs should be prescribed for the shortest possible time. Besides, regular updating of national standard treatment guidelines and health e az gov, use of gastro-protective agents for chronic NSAID users, introduction of electronic medical records for tracing drug interactions and awareness raising programs are highly recommended.

Saleem Basha, Bruk Woldai and Dawit Tesfai health e az gov were involved in the face and content validation of our questionnaire. We also sincerely thank Dr. Luul Banteyrga (Medical Director of Halibet Hospital), Dr. Yosief Yacob (Medical Director of Sembel Hospital) and Dr.

Tsegereda Mehari (Medical Director of Bet-Mekae Community Hospital) who have warmly accepted and approved the study to be conducted in their hospitals. Finally, we would also like to health e az gov all participants of this study for being cooperative in the process.

For more information about PLOS Subject Areas, click here. Is the Subject Area "NSAIDs" applicable to this article. Yes NoIs the Subject Area "Drug interactions" applicable to this article. Yes NoIs the Subject Area "Geriatric care" applicable to this article.

Yes NoIs the Subject Area "Drug-drug interactions" applicable to this article. Yes NoIs the Subject Area "Medical risk factors" applicable to health e az gov article. Yes NoIs the Subject Area "Adverse reactions" applicable to this article. Yes NoIs the Subject Area "Diabetes mellitus" applicable to this article.

Yes NoIs the Subject Area "Antiplatelet therapy" applicable to this article. Learn More Submit Now Browse Subject Areas. Click through the PLOS taxonomy to find articles in your field. Loading metrics Article metrics are unavailable at this time. Article metrics are unavailable for recently published articles. Save Total Mendeley and Citeulike bookmarks. Citation Paper's citation count computed by Dimensions.

View PLOS views and downloads. Share Sum of Facebook, Sleeping drink, Reddit and Wikipedia activity. Health e az gov The author(s) received no specific funding for this work. Materials and methods Study design and setting An analytical cross-sectional study with a quantitative approach was conducted in three selected hospitals Asmara, the capital, namely: Halibet national referral hospital, Sembel hospital (private) and Bet-Mekae community hospital.

Study and source population Elderly patients, aged 60 years and above, taking one or more NSAIDs who attended the study sites during the study period formed the study population. Sampling design In order to get representative samples from each hospital, stratified random sampling was utilized. Data collection tools A data collection form (S1 File) comprising of five sections was used.

Data collection procedure The investigators explained purposes of the study to the participants and those who gave consent were enrolled.

Further...

Comments:

03.09.2019 in 04:59 Bazragore:
It really surprises.

06.09.2019 in 12:57 Nikojind:
I join. All above told the truth. We can communicate on this theme.